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编 号:F504043
分子式:C19H14N2O6
分子量:366.32
产品类型
结构图
CAS No: 891002-11-2
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生物活性:
SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects.