产品
编 号:F503973
分子式:C22H15FN4O3
分子量:402.38
产品类型
结构图
CAS No: 890764-63-3
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产品详情
生物活性:
VU-1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM) with a Ki of 156 nM and an EC50 of 9.6 nM.
体外研究:
VU-1545 (10 and 100 μM) promotes AKT activation. VU-1545 at the concentrations of 0.1 and 1.0 μM efficiently promots Akt activation above basal levels.