产品
编 号：F001061
分子式：C8H6MnNO6S2
分子量：331.2
分子式：C8H6MnNO6S2
分子量：331.2
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 1001015-18-4
产品详情
生物活性：
CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis.
体外研究：
CORM-401 (100 μM; 1h) induces the NO production in endothelial EA.hy926 cells.?CORM-401 (30 μM) induces peak-like calcium signal and augmentes coupling of endoplasmic reticulum and plasmalemmal store-operated calcium channels.?CORM-401 (50 μM; 1h) significantly reduces TNF-α/CHX and H2O2-induced ROS production and cell death.?CORM-401 (0.5, 1 mM) induces a persistent increase in the oxygen consumption rate in endothelial EA.hy926 cells.?CORM-401 (10, 30, 100 μM) induces a concentration-dependent increase in OCR and a simultaneous decrease in ECAR.
CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis.
体外研究：
CORM-401 (100 μM; 1h) induces the NO production in endothelial EA.hy926 cells.?CORM-401 (30 μM) induces peak-like calcium signal and augmentes coupling of endoplasmic reticulum and plasmalemmal store-operated calcium channels.?CORM-401 (50 μM; 1h) significantly reduces TNF-α/CHX and H2O2-induced ROS production and cell death.?CORM-401 (0.5, 1 mM) induces a persistent increase in the oxygen consumption rate in endothelial EA.hy926 cells.?CORM-401 (10, 30, 100 μM) induces a concentration-dependent increase in OCR and a simultaneous decrease in ECAR.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备