产品
编 号：F501397
分子式：C25H26F4N2O2
分子量：462.48
分子式：C25H26F4N2O2
分子量：462.48
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 887375-26-0
产品详情
生物活性：
Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist.
体内研究：
Intradermal injection of compound 48/80 (50 μg in 50 μL saline) resulted in a clear wheal and flare reaction over the 60 min observation period. Topical pre-treatment with mapracorat (0.1%) leads to significant reduction in the wheal and flare responses compared to vehicle (acetone) treated areas.
体外研究：
Mapracorat concentration dependently inhibited TNFα secretion from activated canine PBMC with IC50 value of approximately 0.2 nM.
Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist.
体内研究：
Intradermal injection of compound 48/80 (50 μg in 50 μL saline) resulted in a clear wheal and flare reaction over the 60 min observation period. Topical pre-treatment with mapracorat (0.1%) leads to significant reduction in the wheal and flare responses compared to vehicle (acetone) treated areas.
体外研究：
Mapracorat concentration dependently inhibited TNFα secretion from activated canine PBMC with IC50 value of approximately 0.2 nM.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备