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编 号:F498885
分子式:C23H27FN2O4
分子量:414.47
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结构图
CAS No: 885496-53-7
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生物活性:
S-777469 is a selective and orally available cannabinoid type 2 receptor (CB2) agonist with a Ki of 36 nM. S-777469 significantly suppresses compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 produces its antipruritic effects by inhibiting itch signal transmission through CB2 agonism.