产品
编 号:F497619
分子式:C15H16BrCl3N4
分子量:438.58
产品类型
结构图
CAS No: 885104-09-6
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产品详情
生物活性:
LY2389575 hydrochloride is a selective and noncompetitive mGlu3 negative allosteric modulator (NAM), with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in Mrc1 levels. LY2389575 hydrochloride also independently amplifies Amyloid beta (Aβ) toxicity and can be used in study of Alzheimer's disease.
体外研究:
LY2389575 hydrochloride (5 μM; 1 h) 诱导小胶质细胞中 Mrc1 的水平升高。