产品
编 号：F497421
分子式：C26H31ClF3NO2
分子量：481.98
分子式：C26H31ClF3NO2
分子量：481.98
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 884600-68-4
产品详情
生物活性：
GSM-1 is a potent γ-secretase modulator. GSM-1 directly targets the transmembrane domain (TMD) 1 of presenilin 1 (PS1).
体外研究：
GSM-1 increases the levels of Aβ38 produced from WT APP. GSM-1 potently loweres the levels of Aβ42 of WT APP and all the Phe mutants by ～70–80%, even for the V44F mutant, which produced only extremely small amounts of Aβ42.GSM-1 directly binds to the N-terminal fragment of PS1.
GSM-1 is a potent γ-secretase modulator. GSM-1 directly targets the transmembrane domain (TMD) 1 of presenilin 1 (PS1).
体外研究：
GSM-1 increases the levels of Aβ38 produced from WT APP. GSM-1 potently loweres the levels of Aβ42 of WT APP and all the Phe mutants by ～70–80%, even for the V44F mutant, which produced only extremely small amounts of Aβ42.GSM-1 directly binds to the N-terminal fragment of PS1.
产品资料
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