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编 号:F497157
分子式:C10H14ClNO4
分子量:247.68
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生物活性:
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system.

体内研究:
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.Animal Model:60-day-old male rats
Dosage:200 mg/kg
Administration:I.p.
Result:Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
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