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编 号:F496874
分子式:C30H39N5O7S2
分子量:645.79
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1mg
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5mg
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生物活性:
DPDPE, an opioid peptide, is a selective δ-opioid receptor?(DOR) agonist?with anticonvulsant effects.

体内研究:
DPDPE (70 or 140 nM; i.c.v.; once) shows anticonvulsant effects in rats.DPDPE (0.78–25 μg/mouse; i.c.v.; once) enhances bicuculline-induced convulsions in mouse.Animal Model:Male Sprague-Dawley rats (225-275 g)
Dosage:70 or 140 nM followed by a 2 μl saline flush
Administration:Intracerebroventricular injection
Result:Resulted in a significant, dose-dependent increase in the convulsive threshold to flurothyl.
Animal Model:Male ddY mice weighing 20–30 g, pretreated with 1.5 mg/kg bicuculline (subcutaneous injection).
Dosage:0.78–25 μg/mouse, once
Administration:Intracerebroventricular injection
Result:Caused a dose-dependent increase in the proportion of mice exhibiting convulsions.
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