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编 号:F496105
分子式:C29H28F3N5O2
分子量:535.56
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
AMG-47a is a potent and orally active lymphocyte-specific protein tyrosine kinase (Lck) inhibitor, with an IC50 of 0.2 nM. AMG-47a also inhibits VEGF2, p38α, Jak3 and MLR and IL-2 with IC50s of 1 nM, 3 nM, 72 nM, 30 nM and 21 nM, respectively. AMG-47a has anti-inflammatory activity.
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