产品
编 号:F495059
分子式:C19H24N6O5S2
分子量:480.56
产品类型
结构图
CAS No: 88040-23-7
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产品详情
生物活性:
Cefepime (BMY-28142) is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime induces neurotoxicity.
体内研究:
Cefepime (80 mg/kg; i.p.) significantly increases the half-life and mice surviveed.Animal Model:Male CD-1 mice
Dosage:80 mg/kg
Administration:I.p.
Result:Significantly prolonged the half-life of cefepime and all mice survived at 18-22 mg/kg cisplatin, and when pretreatment with 26 mg/kg cisplatin significantly decreased survival with the half-life of cefepime was not significantly longer than of 18 mg/kg cisplatin.
体外研究:
Cefepime chloride exerts its antibacterial effects by binding to penicillin-binding proteins.