产品
编 号:F493217
分子式:C9H19NO7
分子量:253.25
产品类型
结构图
CAS No: 87-67-2
联系客服
产品详情
生物活性:
Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
体内研究:
Choline bitartrate (oral gavage; 300 mg/kg vs. 5 g/kg) is administrated. Choline restriction (300 mg/kg) provokes robust ketosis and weight loss in mice, also causes significant hepatic steatosis, inflammation, and cellular injury. when Choline is repleted, moderate ketosis and hepatic fat accumulation can be attenuated.
体外研究:
Choline serves as a precursor component to two major cell membrane components: phosphatidylcholine and sphingomyelin in vitro.Choline is also a major source for methyl groups via its metabolite, betaine, which participates in S-adenosylmethionine synthesis pathways.