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编 号:F492610
分子式:C18H33NO4
分子量:327.46
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生物活性:
10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles.

体外研究:
10-Nitrooleic acid (5-25 μM; mouse keratinocytes) regulates expression of HO-1, hsp27, hsp70, Cox-2, and the glutathione-S-transferases GSTA1-2, GSTA3 and GSTA4 in a generally similar manner.10-Nitrooleic acid (10 μM; 0-6 hours) upregulates HO-1 protein in time- and concentration-dependent manners.10-Nitrooleic acid also upregulates protein expression for Cox-2, hsp27, hsp70.
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