产品
编 号:F490569
分子式:C22H17BrO2
分子量:393.27
产品类型
结构图
CAS No: 872201-12-2
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产品详情
生物活性:
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM. K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).
体外研究:
K114's unusually low buffer fluorescence is due to self-quenching in sedimentable aggregates or micelles which upon interacting with amyloid fibrils undergo an enhancement in fluorescence intensity and shifts in the excitation and emission spectra.