产品
编 号:F489338
分子式:C25H20F3N5O2
分子量:479.45
产品类型
结构图
CAS No: 870223-96-4
联系客服
产品详情
生物活性:
AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG-Tie2-1 is a VEGFR2 inhibitor with an IC50 of 3 nM.
体外研究:
AMG-Tie2-1 (compound 15) inhibits Tie-2 phosphorylation in EA.hy926 human endothelial cells (IC50=10 nM).