产品
编 号:F489288
分子式:C19H26N4O4S
分子量:406.5
产品类型
结构图
CAS No: 870070-55-6
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产品详情
生物活性:
Tozadenant is an adenosine A2A receptor antagonist, with Ki of 11.5 nM on human A2A and 6 nM on rhesus A2A.
体内研究:
18F-MNI-444 regional uptake is consistent with A2A receptor distribution in the brain. Selectivity is demonstrated by dose-dependent blocking by tozadenant (1.5, 10.5 mg/kg) and preladenant.