产品
编 号:F489008
分子式:C17H21N5OS
分子量:343.45
产品类型
结构图
CAS No: 869802-58-4
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生物活性:
A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research.