产品
编 号:F488358
分子式:C16H33FO2S
分子量:308.5
产品类型
结构图
CAS No: 86855-26-7
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产品详情
生物活性:
AM 374 is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC50 value of 13 nM. AM 374 can be used for the research of neurological disease.
体内研究:
AM 374 (20 μg;心室内注射,1 次) 对 FR5 杠杆按压无影响,但与 anandamide (腹腔注射) 共同使用时减少杠杆按压。Animal Model:Adult male Sprague-Dawley rats with lever press training
Dosage:20 μg
Administration:Intraventricular (ICV) injection; 20 μg, once
Result:Significantly reduced lever pressing when combined treatment with anandamide.
体外研究:
AM 374 (0-9 nM) 抑制 N18TG2 细胞中 anandamide 分解。