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编 号：F488266
分子式：C12H12N6Na2O10S2
分子量：510.37
分子式：C12H12N6Na2O10S2
分子量：510.37
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CAS No: 86832-68-0
产品详情
生物活性：
Carumonam disodium is a potent antibiotic. Carumonam disodium shows antibacterial activity. Carumonam disodium induces seizure.
体内研究：
Carumonam disodium (1.31-6.89 mmol/kg; i.p.) 诱导 DBA/2、Swiss 和 C57 小鼠癫痫发作。Animal Model:16-24g, 42-48 days DBA/2; 18-28, 42-48 days Swiss and C57 mice
Dosage:1.31-6.89 mmol/kg
Administration:I.p.
Result:Induced seizure in DBA/2, Swiss and C57 mice.
体外研究：
Carumonam disodium (0-100 μg/mL) 表现出抗菌活性，对 Escherichia coli (cefazolin sensitive), Escherichia coli (cefazolin resistant), Klebsiella pneumoniae (cefazolin sensitive), Klebsiella pneumoniae (cefazolin resistant), Klebsiella oxytoca, Enterobacter cloacae, Serratia marcescens (gentamicin sensitive), Serratia marcescens (gentamicin resistant), Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri, Proteus inconstans 的 MIC90 值分别为 0.2, 3.13, 0.2, 0.39, 0.2, 6.25, 0.2, 3.13, 0.05, 0.025, 0.78, 0.013, 0.025 μg/mL。
Carumonam disodium is a potent antibiotic. Carumonam disodium shows antibacterial activity. Carumonam disodium induces seizure.
体内研究：
Carumonam disodium (1.31-6.89 mmol/kg; i.p.) 诱导 DBA/2、Swiss 和 C57 小鼠癫痫发作。Animal Model:16-24g, 42-48 days DBA/2; 18-28, 42-48 days Swiss and C57 mice
Dosage:1.31-6.89 mmol/kg
Administration:I.p.
Result:Induced seizure in DBA/2, Swiss and C57 mice.
体外研究：
Carumonam disodium (0-100 μg/mL) 表现出抗菌活性，对 Escherichia coli (cefazolin sensitive), Escherichia coli (cefazolin resistant), Klebsiella pneumoniae (cefazolin sensitive), Klebsiella pneumoniae (cefazolin resistant), Klebsiella oxytoca, Enterobacter cloacae, Serratia marcescens (gentamicin sensitive), Serratia marcescens (gentamicin resistant), Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri, Proteus inconstans 的 MIC90 值分别为 0.2, 3.13, 0.2, 0.39, 0.2, 6.25, 0.2, 3.13, 0.05, 0.025, 0.78, 0.013, 0.025 μg/mL。
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