产品
编 号：F488203
分子式：C24H24N2O7
分子量：452.46
分子式：C24H24N2O7
分子量：452.46
产品类型
规格
价格
是否有货
5mg
询价
询价
结构图
CAS No: 868224-64-0
产品详情
生物活性：
SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily.
体外研究：
SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively.SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM.
SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily.
体外研究：
SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively.SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM.
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