产品
编 号：F488123
分子式：C9H16NNaO5
分子量：241.22
分子式：C9H16NNaO5
分子量：241.22
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
400
In-stock
500mg
720
In-stock
结构图
CAS No: 867-81-2
产品详情
生物活性：
D-Pantothenic acid sodium (Sodium pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid sodium plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism.
体内研究：
泛酸 (PTA；3x10、3x100 和 3x300 mg/kg) 降低丙戊酸 (VPA；300、400 和 500 mg/kg，sc) 诱导的小鼠神经管缺陷。Animal Model:Female ICR mice weighing 29-35 g
Dosage:3x10, 3x100, and 3x300 mg/kg (10 mL/kg, volume administered)
Administration:Injected intraperitoneally (i.p.) on day 8.5 of gestation
Result:Significantly reduced VPA (300, 400, and 500 mg/kg, s.c.)-induced exencephaly, while none of the other external malformations such as open eyelid or skeletal malformations such as fused, absent, or bifurcated ribs and fused thoracic vertebrae and fused sternebrae were reduced.
体外研究：
D-Pantothenic acid sodium 是辅酶 A 的前体，主要分别通过 TCA 循环和 β-氧化途径参与能量产生和脂质代谢。
D-Pantothenic acid sodium (Sodium pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid sodium plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism.
体内研究：
泛酸 (PTA；3x10、3x100 和 3x300 mg/kg) 降低丙戊酸 (VPA；300、400 和 500 mg/kg，sc) 诱导的小鼠神经管缺陷。Animal Model:Female ICR mice weighing 29-35 g
Dosage:3x10, 3x100, and 3x300 mg/kg (10 mL/kg, volume administered)
Administration:Injected intraperitoneally (i.p.) on day 8.5 of gestation
Result:Significantly reduced VPA (300, 400, and 500 mg/kg, s.c.)-induced exencephaly, while none of the other external malformations such as open eyelid or skeletal malformations such as fused, absent, or bifurcated ribs and fused thoracic vertebrae and fused sternebrae were reduced.
体外研究：
D-Pantothenic acid sodium 是辅酶 A 的前体，主要分别通过 TCA 循环和 β-氧化途径参与能量产生和脂质代谢。
产品资料
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