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编 号:F488056
分子式:C21H13BrCl2FN3O4S
分子量:573.22
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CAS No: 867365-76-2
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RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.