产品
编 号:F486318
分子式:C18H16ClF3N2OS
分子量:400.85
产品类型
结构图
CAS No: 864716-85-8
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产品详情
生物活性:
Mesendogen is a TRPM6 inhibitor. Mesendogen enhances the mesoderm and definitive endoderm (DE) differentiations of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs). Mesendogen can be used for the research of magnesium homeostasis during early embryonic cell development.
体外研究:
Mesendogen (10 μM) 诱导人类胚胎干细胞中胚层和内胚层分化,降低神经分化标志物的水平.Mesendogen (2.5,10 和 25 μM;过夜) 剂量依赖性地降低 H1 人类胚胎干细胞的细胞内镁水平.Mesendogen (10 μM;7 天) 抑制 Dorsomorphin 诱导的神经分化活性。