产品
编 号：F486016
分子式：C4H4Na3O6P
分子量：248.01
分子式：C4H4Na3O6P
分子量：248.01
产品类型
规格
价格
是否有货
2mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 864167-45-3
产品详情
生物活性：
Succinyl phosphonate trisodium salt is an α-ketoglutarate dehydrogenase (KGDHC) inhibitor, effective inhibits (KGDHC) in muscle, bacterial, brain, and cultured human fibroblasts. Succinyl phosphonate trisodium salt is an 2-oxoglutarate dehydrogenase (OGDH) inhibitor, impairs viability of cancer cells in a cell-specific metabolism-dependent manner. Succinyl phosphonate trisodium salt inhibits the glutamate-induced ROS production in glutamate-stimulated hippocampal neurons in situ.
体内研究：
Succinyl phosphonate trisodium salt (0.02 mmol/kg, 鼻腔给药) 可抑制大鼠脑 2-氧戊二酸脱氢酶降低谷胱甘肽氧化还原状态，提高焦虑和干扰应激适应。
Succinyl phosphonate trisodium salt is an α-ketoglutarate dehydrogenase (KGDHC) inhibitor, effective inhibits (KGDHC) in muscle, bacterial, brain, and cultured human fibroblasts. Succinyl phosphonate trisodium salt is an 2-oxoglutarate dehydrogenase (OGDH) inhibitor, impairs viability of cancer cells in a cell-specific metabolism-dependent manner. Succinyl phosphonate trisodium salt inhibits the glutamate-induced ROS production in glutamate-stimulated hippocampal neurons in situ.
体内研究：
Succinyl phosphonate trisodium salt (0.02 mmol/kg, 鼻腔给药) 可抑制大鼠脑 2-氧戊二酸脱氢酶降低谷胱甘肽氧化还原状态，提高焦虑和干扰应激适应。
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