产品
编 号:F485343
分子式:C34H32FN5Na2O7
分子量:687.63
产品类型
结构图
CAS No: 862583-15-1
联系客服
产品详情
生物活性:
Gastrazole (JB95008) is potent and selective CCK2/gastrin receptor antagonist. Gastrazole can decrease the level of gastric acid. Gastrazole inhibits the Gastrin-stimulated growth of pancreatic cancer.
体内研究:
Gastrazole (0.15-3 μmol/kg; i.v.) dose-dependently inhibits the Pentagastrin-stimulated gastric acid secretion.Animal Model:Male Sprague-Dawley rats with a gastric fistula
Dosage:0.15, 0.3, 3 mg/kg
Administration:Intravenous administration
Result:Dose-dependently inhibited Pentagastrin-stimulation acid secretion by maximally 73%.