产品
编 号：F485232
分子式：C22H34O2
分子量：330.5
分子式：C22H34O2
分子量：330.5
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
50mg
480
In-stock
100mg
800
In-stock
500mg
2800
In-stock
结构图
CAS No: 86227-47-6
产品详情
生物活性：
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats.
体内研究：
Eicosapentaenoic acid ethyl ester (300 mg/kg, 口服, 持续 4 周) 可抑制 1-methyl-2-imidazolethiol (MMI) 诱导的甲状腺功能减退大鼠甲状腺激素水平的降低和甲状腺滤泡的改变。Eicosapentaenoic acid ethyl ester (1 g/kg, 灌胃, 持续 5 周) 可逆转高脂肪饮食大鼠血浆胆固醇水平的升高，并降低循环甘油三酯水平。Animal Model:MMI-Induced hypothyroid rats
Dosage:300 mg/kg
Administration:p.o. for 4 weeks
Result:Elevated the levels of EPA, T3 and T4
Animal Model:Lean and overweight (high-fat-fed) rats
Dosage:1 g/kg
Administration:i.g. for 5 weeks
Result:Decreased the levels of cholesterol and TG.
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats.
体内研究：
Eicosapentaenoic acid ethyl ester (300 mg/kg, 口服, 持续 4 周) 可抑制 1-methyl-2-imidazolethiol (MMI) 诱导的甲状腺功能减退大鼠甲状腺激素水平的降低和甲状腺滤泡的改变。Eicosapentaenoic acid ethyl ester (1 g/kg, 灌胃, 持续 5 周) 可逆转高脂肪饮食大鼠血浆胆固醇水平的升高，并降低循环甘油三酯水平。Animal Model:MMI-Induced hypothyroid rats
Dosage:300 mg/kg
Administration:p.o. for 4 weeks
Result:Elevated the levels of EPA, T3 and T4
Animal Model:Lean and overweight (high-fat-fed) rats
Dosage:1 g/kg
Administration:i.g. for 5 weeks
Result:Decreased the levels of cholesterol and TG.
产品资料
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