产品
编 号：F485148
分子式：C20H15ClNO4PS
分子量：431.83
分子式：C20H15ClNO4PS
分子量：431.83
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规格
价格
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CAS No: 862090-74-2
产品详情
生物活性：
Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM.
体内研究：
Chymase-IN-1 exhibits low oral bioavailability in rats (F=3%; oral t1/2=1.8 h).
体外研究：
Chymase-IN-1 (compound 5f) is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Results demonstrate that Chymase-IN-1 has a chymase Ki value of 36 nM and a Cat G Ki value of 9500 nM.
Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM.
体内研究：
Chymase-IN-1 exhibits low oral bioavailability in rats (F=3%; oral t1/2=1.8 h).
体外研究：
Chymase-IN-1 (compound 5f) is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Results demonstrate that Chymase-IN-1 has a chymase Ki value of 36 nM and a Cat G Ki value of 9500 nM.
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