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编 号：F485141
分子式：C22H28O9S
分子量：468.52
分子式：C22H28O9S
分子量：468.52
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CAS No: 862073-79-8
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生物活性：
Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice.
体内研究：
Mesyl Salvinorin B (0.3, 1, 3 mg/kg; i.p.; once) 3 mg/kg 时可在雄性和雌性小鼠中预防ADE。Animal Model:8 weeks, Male and female adult C57BL/6J mice
Dosage:0.3, 1, 3 mg/kg
Administration:I.p.; once
Result:Showed less intake than the vehicle-treated ones in the ADE (Alcohol deprivation effect) session at 3 mg/kg.
Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice.
体内研究：
Mesyl Salvinorin B (0.3, 1, 3 mg/kg; i.p.; once) 3 mg/kg 时可在雄性和雌性小鼠中预防ADE。Animal Model:8 weeks, Male and female adult C57BL/6J mice
Dosage:0.3, 1, 3 mg/kg
Administration:I.p.; once
Result:Showed less intake than the vehicle-treated ones in the ADE (Alcohol deprivation effect) session at 3 mg/kg.
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