产品
编 号:F485092
分子式:C19H23N3O2
分子量:325.4
产品类型
结构图
CAS No: 861891-50-1
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产品详情
生物活性:
IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death.
体外研究:
IM-54 选择性抑制氧化应激诱导的坏死,但不抑制各种抗癌药物或Fas配体诱导的细胞凋亡,或坏死性凋亡。 IM-54 对H2O2-诱导细胞坏死,在 HL-60 细胞中的 IC50 为 0.25 μM。