产品
编 号：F484069
分子式：C19H15ClFNO2S
分子量：375.84
分子式：C19H15ClFNO2S
分子量：375.84
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 860033-06-3
产品详情
生物活性：
L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite.
体内研究：
L 888607 (i.v., 5 mg/kg, single or oral, 20 mg/kg, single) shows relative stability in vivo.Animal Model:Male (ICR)BR mice
Dosage:5 mg/kg, 20 mg/kg
Administration:i.v., 5 mg/kg, single or oral, 20 mg/kg, single
Result:Showed no obvious side effect.
体外研究：
L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM.L 888607 has some affinity for the human DP receptor with a Ki value of 211 nM.L 888607 displays a relatively high selectivity for CRTH2 receptor.L 888607 has agonistic activity on recombinant and endogenously expressed CRTH2 receptor with an EC50 value of 0.4 nM.L 888607(100 nM, 20 min) stimulates eosinophil chemotaxis.
L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite.
体内研究：
L 888607 (i.v., 5 mg/kg, single or oral, 20 mg/kg, single) shows relative stability in vivo.Animal Model:Male (ICR)BR mice
Dosage:5 mg/kg, 20 mg/kg
Administration:i.v., 5 mg/kg, single or oral, 20 mg/kg, single
Result:Showed no obvious side effect.
体外研究：
L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM.L 888607 has some affinity for the human DP receptor with a Ki value of 211 nM.L 888607 displays a relatively high selectivity for CRTH2 receptor.L 888607 has agonistic activity on recombinant and endogenously expressed CRTH2 receptor with an EC50 value of 0.4 nM.L 888607(100 nM, 20 min) stimulates eosinophil chemotaxis.
产品资料
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