产品
编 号:F482705
分子式:C17H16FN6O6P
分子量:450.32
产品类型
结构图
CAS No: 856867-55-5
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产品详情
生物活性:
Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.
体内研究:
For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.
体外研究:
Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.