产品
编 号：F482141
分子式：C26H32O7
分子量：456.53
分子式：C26H32O7
分子量：456.53
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CAS No: 855746-98-4
产品详情
生物活性：
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase.
体内研究：
Kurarinol (20 mg/kg; p.o.; daily; for 3 days) reduces serum lipid levels in high-Cholesterol diet induced hyperlipidemic rats.Animal Model:Male Sprague-Dawley rats (120-130g), hypercholesterolemic models
Dosage:20 mg/kg
Administration:Oral administration, daily, for 3 days
Result:Decreased serum TC, TG, and LDL-C levels.
体外研究：
Kurarinol manifests relatively low cytotoxic activity (EC50>30 μM).Kurarinol inhibits production of melanin in S. bikiniensis without affecting the growth of microorganism.Kurarinol induces hepatocellular carcinoma cell apoptosis through suppressing cellular signal transducer and activator of transcription 3 signaling (STAT3).
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase.
体内研究：
Kurarinol (20 mg/kg; p.o.; daily; for 3 days) reduces serum lipid levels in high-Cholesterol diet induced hyperlipidemic rats.Animal Model:Male Sprague-Dawley rats (120-130g), hypercholesterolemic models
Dosage:20 mg/kg
Administration:Oral administration, daily, for 3 days
Result:Decreased serum TC, TG, and LDL-C levels.
体外研究：
Kurarinol manifests relatively low cytotoxic activity (EC50>30 μM).Kurarinol inhibits production of melanin in S. bikiniensis without affecting the growth of microorganism.Kurarinol induces hepatocellular carcinoma cell apoptosis through suppressing cellular signal transducer and activator of transcription 3 signaling (STAT3).
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