产品
编 号:F480569
分子式:C10H20BN3O3
分子量:241.1
产品类型
结构图
CAS No: 852329-66-9
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产品详情
生物活性:
Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
体内研究:
Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a Tmax of 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s.