产品
编 号：F477063
分子式：C18H28N2O7
分子量：384.42
分子式：C18H28N2O7
分子量：384.42
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
50mg
480
In-stock
100mg
840
In-stock
500mg
询价
询价
结构图
CAS No: 84680-54-6
产品详情
生物活性：
Enalaprilat dihydrate (MK-422), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat dihydrate can be used for the research of hypertension.
体内研究：
Enalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP)-lowering effect in rabbits.
体外研究：
Enalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.
Enalaprilat dihydrate (MK-422), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat dihydrate can be used for the research of hypertension.
体内研究：
Enalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP)-lowering effect in rabbits.
体外研究：
Enalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.
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