产品
编 号:F476010
分子式:C28H27NO4S
分子量:473.58
产品类型
结构图
CAS No: 84449-90-1
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产品详情
生物活性:
Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research.
体内研究:
Raloxifene (4?mg/kg; intragastrically; daily for 13 weeks) significantly prevents bone loss in ovariectomized (OVX) rats.Animal Model:Female, 12-week-old, Wistar rats (OVX rats)
Dosage:4?mg/kg
Administration:Intragastrically; daily for 13 weeks
Result:Significantly increased the levels of E2 in OVX rats and significantly decreased the levels of BGP.