产品
编 号：F475961
分子式：C12H6Cl4O3S
分子量：372.05
分子式：C12H6Cl4O3S
分子量：372.05
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
结构图
CAS No: 844-26-8
产品详情
生物活性：
Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection.
体内研究：
Bithionol sulfoxide (oral administration) shows LD50 values of 1000-5000 mg/kg (mice) and about 5000 mg/kg (rats), and increased serum AST at high doses (5000-100 mg/kg).Bithionol sulfoxide (80 and 90 mg/kg, oral administration) is effective against natural rumen fluke infections in dairy cattle.Animal Model:Dairy cattle
Dosage:60, 80 90 mg/kg
Administration:Oral administration
Result:Showed approximately 70% effective against rumen flukes infection at dosages of 80 and 90 mg/kg after one week post treatment.
体外研究：
Bithionol sulfoxide (0.1-10 mg/mL, 72 h) shows toxicity to Neoparamoeba spp parasites in sea water.Bithionol sulfoxide (1-1000 μg/plate) exhibits mutagenic activity, in the absence of metabolic activation, in strains TA98 and TA100 (in Salmonella/mammalian microsome test).
Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection.
体内研究：
Bithionol sulfoxide (oral administration) shows LD50 values of 1000-5000 mg/kg (mice) and about 5000 mg/kg (rats), and increased serum AST at high doses (5000-100 mg/kg).Bithionol sulfoxide (80 and 90 mg/kg, oral administration) is effective against natural rumen fluke infections in dairy cattle.Animal Model:Dairy cattle
Dosage:60, 80 90 mg/kg
Administration:Oral administration
Result:Showed approximately 70% effective against rumen flukes infection at dosages of 80 and 90 mg/kg after one week post treatment.
体外研究：
Bithionol sulfoxide (0.1-10 mg/mL, 72 h) shows toxicity to Neoparamoeba spp parasites in sea water.Bithionol sulfoxide (1-1000 μg/plate) exhibits mutagenic activity, in the absence of metabolic activation, in strains TA98 and TA100 (in Salmonella/mammalian microsome test).
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