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编 号:F475141
分子式:C18H22O2
分子量:270.37
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10mM*1mL in DMSO
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50mg
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生物活性:
Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle.

体内研究:
Hexestrol (3 and 6 mg/kg; i.p. once daily for 30 days) has a not significant influence in the ovaries from mice at the dose of 3 mg/kg.Animal Model:Mus musculus (90-120 days, 25-50 g)
Dosage:3, 6 mg/kg (adopted the same dose used to increase weight gain in cattle)
Administration:I.p. once daily for 30 days
Result:Numerous follicles in different stages of development were found at the dose of 3 mg/kg in the ovaries.Not detected the corpora lutea (CL) at the dose of 6 mg/kg.
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