产品
编 号：F474202
分子式：C32H39NO4
分子量：501.66
分子式：C32H39NO4
分子量：501.66
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
结构图
CAS No: 83799-24-0
产品详情
生物活性：
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research.
体内研究：
Fexofenadine hydrochloride (oral administration; 5-20 mg/kg; once daily; 3 w) suppresses both eosinophilia and systemic anaphylaxis in C57BL/6 mice infected with T. spiralis.Animal Model:C57BL/6 mice infected with Trichinella spiralis
Dosage:5, 10 and 20 mg/kg
Administration:Oral administration; 5, 10 and 20 mg/kg; once daily; 3 weeks
Result:Inhibited eosinophilia in a dose-dependent manner.Suppressed the decrease in rectal temperature (p<0.01), a marker for systemic anaphylaxis.
体外研究：
Fexofenadine (1-100 μM; 1 h) inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner.Fexofenadine (1-100 μM; 1 h) blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts, but shows no effect on either pERK or pJNK.
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research.
体内研究：
Fexofenadine hydrochloride (oral administration; 5-20 mg/kg; once daily; 3 w) suppresses both eosinophilia and systemic anaphylaxis in C57BL/6 mice infected with T. spiralis.Animal Model:C57BL/6 mice infected with Trichinella spiralis
Dosage:5, 10 and 20 mg/kg
Administration:Oral administration; 5, 10 and 20 mg/kg; once daily; 3 weeks
Result:Inhibited eosinophilia in a dose-dependent manner.Suppressed the decrease in rectal temperature (p<0.01), a marker for systemic anaphylaxis.
体外研究：
Fexofenadine (1-100 μM; 1 h) inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner.Fexofenadine (1-100 μM; 1 h) blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts, but shows no effect on either pERK or pJNK.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备