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编 号：F473044
分子式：C26H32N2O5
分子量：452.54
分子式：C26H32N2O5
分子量：452.54
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CAS No: 83435-66-9
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生物活性：
Delapril (CV-3317) is an orally active angiotensin I converting enzyme (ACE) inhibitor. Delapril has antihypertensive activity.
体内研究：
Delapril (5-20 mg/kg，饮用水喂养) 可减缓胆固醇喂养兔的动脉粥样硬化进展。Delapril (1-10 mg/kg，p.o.，每日一次，持续 5 周) 在高血压大鼠中表现出自发的抗高血压作用。Animal Model:Cholesterol-fed rabbits
Dosage:5 mg/kg at D5, 10 mg/kg at D10, 20 mg/kg at D20
Administration:Fed in a fixed volume (10 ml) of drinking water
Result:Decreased aortic area covered by lesions.Restored endothelium-dependent relaxation
Delapril (CV-3317) is an orally active angiotensin I converting enzyme (ACE) inhibitor. Delapril has antihypertensive activity.
体内研究：
Delapril (5-20 mg/kg，饮用水喂养) 可减缓胆固醇喂养兔的动脉粥样硬化进展。Delapril (1-10 mg/kg，p.o.，每日一次，持续 5 周) 在高血压大鼠中表现出自发的抗高血压作用。Animal Model:Cholesterol-fed rabbits
Dosage:5 mg/kg at D5, 10 mg/kg at D10, 20 mg/kg at D20
Administration:Fed in a fixed volume (10 ml) of drinking water
Result:Decreased aortic area covered by lesions.Restored endothelium-dependent relaxation
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