产品
编 号：F472752
分子式：C9H9N
分子量：131.17
分子式：C9H9N
分子量：131.17
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1g
144
In-stock
5g
询价
询价
结构图
CAS No: 83-34-1
产品详情
生物活性：
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream.
体外研究：
Skatole (0-1000 μM, 0-72 h) 时间和剂量依赖性地诱导肠上皮细胞凋亡。Skatole (1000 μM) 显著激活 AhR (48 h) 和 p38 (30 min)。Skatole (10 μM, 24 h) 可显著逆转 Irisin 对 Ang II 诱导的 VSMC 增殖、迁移和表型转化的抑制作用。
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream.
体外研究：
Skatole (0-1000 μM, 0-72 h) 时间和剂量依赖性地诱导肠上皮细胞凋亡。Skatole (1000 μM) 显著激活 AhR (48 h) 和 p38 (30 min)。Skatole (10 μM, 24 h) 可显著逆转 Irisin 对 Ang II 诱导的 VSMC 增殖、迁移和表型转化的抑制作用。
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