产品
编 号:F472244
分子式:C21H32N4O6
分子量:436.5
产品类型
结构图
CAS No: 83209-65-8
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产品详情
生物活性:
HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC50 of 30 nM. HC-Toxin induces tumor cell apoptosis and has anticancer effects.
体外研究:
HC-Toxin shows potent antiproliferative efficacy and cell cycle arrest at G2/M in T47D human breast cancer cells in a dose-dependent manner. HC-Toxin evokes apoptosis of T47D cells and HC-toxin induced apoptosis might not be mediated through direct increase in caspase-3/7 activity.