产品
编 号：F470130
分子式：C20H22O9
分子量：406.39
分子式：C20H22O9
分子量：406.39
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
250
In-stock
10mg
400
In-stock
25mg
800
In-stock
50mg
1120
In-stock
结构图
CAS No: 82373-94-2
产品详情
生物活性：
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions.
体内研究：
2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside (30-60 mg/kg, 腹腔注射, 每日一次, 7 天) 可通过抑制神经炎症和氧化亚硝化应激来应对雄性 ICR 小鼠抑郁样症状。Animal Model:Male ICR mice
Dosage:30-60 mg/kg
Administration:i.p., daily, 7 days
Result:Inhibited the production of proinflammatory cytokines induced by LPS, such as interleukin-1β, interleukin-6, and tumor necrosis factor-α.Prevented the LPS-induced enhancement of oxido-nitrosative stress in mouse hippocampus and prefrontal cortex.Prevented LPS-induced decreases in brain-derived neurotrophic factor levels in the hippocampus and prefrontal cortex.
体外研究：
2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside (5-80 μM, 2 h) 抑制 RAW264.7 细胞中 LPS 诱导的促炎细胞因子 (IL-6 和 TNF-α) 的表达。2,3,4',5-tetraHydroxystilbene 2-O-D-glucoside (5-80 μM, 2 h) 抑制RAW264.7 细胞中 NO 表达和促炎细胞因子 (IL-1β、IL-6、TNF-α 和 COX-2) 的 mRNA 水平。2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside (5-80 μM, 2 h) 抑制 LPS 诱导的 RAW264.7 细胞中 NF-κB 信号通路和 ERK2 活化。
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions.
体内研究：
2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside (30-60 mg/kg, 腹腔注射, 每日一次, 7 天) 可通过抑制神经炎症和氧化亚硝化应激来应对雄性 ICR 小鼠抑郁样症状。Animal Model:Male ICR mice
Dosage:30-60 mg/kg
Administration:i.p., daily, 7 days
Result:Inhibited the production of proinflammatory cytokines induced by LPS, such as interleukin-1β, interleukin-6, and tumor necrosis factor-α.Prevented the LPS-induced enhancement of oxido-nitrosative stress in mouse hippocampus and prefrontal cortex.Prevented LPS-induced decreases in brain-derived neurotrophic factor levels in the hippocampus and prefrontal cortex.
体外研究：
2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside (5-80 μM, 2 h) 抑制 RAW264.7 细胞中 LPS 诱导的促炎细胞因子 (IL-6 和 TNF-α) 的表达。2,3,4',5-tetraHydroxystilbene 2-O-D-glucoside (5-80 μM, 2 h) 抑制RAW264.7 细胞中 NO 表达和促炎细胞因子 (IL-1β、IL-6、TNF-α 和 COX-2) 的 mRNA 水平。2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside (5-80 μM, 2 h) 抑制 LPS 诱导的 RAW264.7 细胞中 NF-κB 信号通路和 ERK2 活化。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备