产品
编 号：F469708
分子式：C18H19ClN4O2
分子量：358.82
分子式：C18H19ClN4O2
分子量：358.82
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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2mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 821794-90-5
产品详情
生物活性：
CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.
体外研究：
CMK inhibits the growth of Cdc5 (L158G) with IC50 of 36 nM, greater than 30 μM for wild type Cdc5. CMK exhibits a concentration-dependent first cell cycle mitotic arrest in the cdc5-as1 strain with an IC50 of 1.1 μM. CMK inhibition of Cdc5 (L158G) leads to a first cell cycle anaphase arrest and delay in anaphase spindle migration.
CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.
体外研究：
CMK inhibits the growth of Cdc5 (L158G) with IC50 of 36 nM, greater than 30 μM for wild type Cdc5. CMK exhibits a concentration-dependent first cell cycle mitotic arrest in the cdc5-as1 strain with an IC50 of 1.1 μM. CMK inhibition of Cdc5 (L158G) leads to a first cell cycle anaphase arrest and delay in anaphase spindle migration.
产品资料
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