产品
编 号：F055435
分子式：C23H15ClF2N4O3
分子量：468.84
分子式：C23H15ClF2N4O3
分子量：468.84
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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50mg
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结构图
CAS No: 1174046-72-0
产品详情
生物活性：
BMS-794833 is a VEGFR2 and Met inhibitor extracted from patent WO2009094417, compound example 1; has IC50s of 15 and 1.7 nM, respectively.
体内研究：
BMS-794833 is active by greater than 50% tumor growth inhibition for at least one tumor doubling time in the GTL-16 gastric carcinoma model. No toxicity is observed at any of the dose levels when administered once daily for a duration of 14 days.
体外研究：
BMS794833 inhibits Met receptor activated gastric carcinoma cell line, GTL-16, with an IC50 of 39 nM.
BMS-794833 is a VEGFR2 and Met inhibitor extracted from patent WO2009094417, compound example 1; has IC50s of 15 and 1.7 nM, respectively.
体内研究：
BMS-794833 is active by greater than 50% tumor growth inhibition for at least one tumor doubling time in the GTL-16 gastric carcinoma model. No toxicity is observed at any of the dose levels when administered once daily for a duration of 14 days.
体外研究：
BMS794833 inhibits Met receptor activated gastric carcinoma cell line, GTL-16, with an IC50 of 39 nM.
产品资料
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