产品
编 号:F468679
分子式:C35H51N9O8
分子量:725.83
产品类型
结构图
CAS No: 81733-79-1
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产品详情
生物活性:
Dalargin is a potent δ-opioid receptor agonist. Dalargin mitigates Gentamicin (HY-A0276)-induced cell death. Dalargin shows nephroprotective effects on Gentamicin-induced kidney injury. Dalargin shows antiulcer activity.
体内研究:
Dalargin (25, 50 μg/kg; i.p.) 对庆大霉素诱导的大鼠肾损伤显示出肾脏保护作用。Animal Model:290-350 g, White male rats
Dosage:25, 50 μg/kg
Administration:I.p. (3 h before each gentamicin injection)
Result:Mitigated gentamicin-induced acutekidney injury, attenuated ROS generation and oxidative stress, alleviated histopathological changes in a renal tissue.
体外研究:
Dalargin (100 μg/mL; 1 h) 在体外减轻庆大霉素诱导的肾上皮细胞死亡。