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编 号:F467319
分子式:C35H67N17O11
分子量:902.01
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1mg
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5mg
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生物活性:
PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG).

体外研究:
Incorporation of [33P]ATP into the synthetic peptide PKG substrate RKRSRAE is measured. N6-benzyl-ATP inhibits kinase activity of PKG Iα gatekeeper mutants but not WT. The serotonin transporter (SERT) is responsible for reuptake of serotonin (5-hydroxytryptamine) after its exocytotic release from neurons. SERT is regulated by several processes, including a cyclic GMP signaling pathway involving nitric oxide synthase, guanylyl cyclase, and PKG.
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