产品
编 号:F465535
分子式:C36H36N2O8
分子量:624.68
产品类型
结构图
CAS No: 80510-06-1
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产品详情
生物活性:
Grossamide is a natural product that can be isolated from fructus cannabis, the dried fruit of Cannabis sativa L.. Grossamide has anti-neuroinflammatory effects.
体外研究:
Grossamide downregulates LPS-mediated production of inflammatory molecules.Grossamide (0-20 μM, 1 h) inhibits the mRNA levels of TNF-α and IL-6 in a dose-dependent manner, inhibits LPS-induced NF-κB activation, and inhibits LPS-induced TLR4 and MyD88 expression without cytotoxicity.