产品
编 号：F465526
产品类型
规格
价格
是否有货
10g
480
In-stock
50g
1280
In-stock
结构图
CAS No: 8050-81-5
产品详情
生物活性：
Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic.
体内研究：
Simethicone (200 mg/kg；口服；单剂量) 在大鼠中具有肠胃调节功能。Simethicone (20 mg/kg；口服；单剂量) 在兔子中显示出空肠调节作用。Animal Model:Female adult Wistar rats (200–250 g).
Dosage:50, 100 and 200 mg/kg.
Administration:Oral gavage; single dose.
Result:Improved colon permeability and hypersensitivity (200 mg/kg).
Animal Model:Adult New Zealand White (NZW) rabbits.
Dosage:20 mg/kg.
Administration:Oral gavage; single dose.
Result:Improved image quality scores for the jejunum without affecting left kidney, right kidney and gallbladder.
Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic.
体内研究：
Simethicone (200 mg/kg；口服；单剂量) 在大鼠中具有肠胃调节功能。Simethicone (20 mg/kg；口服；单剂量) 在兔子中显示出空肠调节作用。Animal Model:Female adult Wistar rats (200–250 g).
Dosage:50, 100 and 200 mg/kg.
Administration:Oral gavage; single dose.
Result:Improved colon permeability and hypersensitivity (200 mg/kg).
Animal Model:Adult New Zealand White (NZW) rabbits.
Dosage:20 mg/kg.
Administration:Oral gavage; single dose.
Result:Improved image quality scores for the jejunum without affecting left kidney, right kidney and gallbladder.
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