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编 号:F465512
分子式:C17H32BrNO2
分子量:362.35
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生物活性:
Anisotropine (Octatropine) bromide is an orally active anticholinergic muscarinic antagonist. Anisotropine bromide can inhibit gastric acid secretion and is used as an adjunct to peptic ulcers.

体内研究:
Anisotropine bromide (intravenous injection, 0.5 μM and 0.1 mL, once) can block acetylcholine-induced vocalization, intestinal spasm and intestinal contractions in conscious or anesthetized dogs.Animal Model:Dogs weighing 2.5 to 5.0 kg
Dosage:0.5 μM, 0.1 mL
Administration:Intravenous injection; once
Result:Inhibited the acetylcholine-induced vocalization with maximum inhibition of 85.1% and the acetylcholine-induced intestinal spasm with maximum inhibition of 79%.
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