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编 号：F463121
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50mL
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CAS No: 8001-30-7
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生物活性：
Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.
体内研究：
用 Corn oil 灌胃的大鼠血清生长激素 (GH) 水平降低了 54%，通过渗透性微型泵输注将 GH 替换为用 Corn oil 灌胃的大鼠，原位 MNCL 细胞增殖增加到水灌胃动物中观察到的速率。在动物研究环境中，Corn oil 通常用作饲料添加剂或亲脂性物质的运载工具。玉米油可能会被污染，并在腹腔注射几天后导致死亡/全身感染，因此玉米油应等分并冷冻（建议）； 每次解冻并制成新鲜溶液。Corn oil 更推荐用于灌胃。腹腔内涂抹 Corn oil 会导致局部炎症，同时消耗常驻腹腔巨噬细胞。Animal Model:Female C57BL/6J mice (n = 90; age, 6 to 7 wk)
Dosage:0.1 mL.
Administration:Intraperitoneal injection every 48 h for a total of 4 injections over a 7-d period.
Result:At day 21, pharmaceutical-grade (PG) corn oil had a significantly higher pathology score compared with nonpharmaceutical-grade corn oil. No other significant differences between the corn oil groups were observed. The use of nonpharmaceutical grade corn oil did not result in adverse clinical consequences and is presumed safe to use for intraperitoneal injection in mice.
Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.
体内研究：
用 Corn oil 灌胃的大鼠血清生长激素 (GH) 水平降低了 54%，通过渗透性微型泵输注将 GH 替换为用 Corn oil 灌胃的大鼠，原位 MNCL 细胞增殖增加到水灌胃动物中观察到的速率。在动物研究环境中，Corn oil 通常用作饲料添加剂或亲脂性物质的运载工具。玉米油可能会被污染，并在腹腔注射几天后导致死亡/全身感染，因此玉米油应等分并冷冻（建议）； 每次解冻并制成新鲜溶液。Corn oil 更推荐用于灌胃。腹腔内涂抹 Corn oil 会导致局部炎症，同时消耗常驻腹腔巨噬细胞。Animal Model:Female C57BL/6J mice (n = 90; age, 6 to 7 wk)
Dosage:0.1 mL.
Administration:Intraperitoneal injection every 48 h for a total of 4 injections over a 7-d period.
Result:At day 21, pharmaceutical-grade (PG) corn oil had a significantly higher pathology score compared with nonpharmaceutical-grade corn oil. No other significant differences between the corn oil groups were observed. The use of nonpharmaceutical grade corn oil did not result in adverse clinical consequences and is presumed safe to use for intraperitoneal injection in mice.
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